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Could a Boots cold remedy made from seaweed help prevent COVID-19? A Swansea University study aims to find out.

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A Swansea University research study of NHS frontline workers is underway to investigate if seaweed could be a powerful ally in preventing COVID-19.

The study of 480 frontline Swansea NHS workers by Swansea University investigates the efficacy of an over the counter cold remedy from high street chemist Boots, in preventing COVID-19 illness and reducing the severity of COVID-19 symptoms.

Boots Dual Defence which contains Carragelose, a patented version of iota-carrageenan and a form of seaweed, is already clinically proven to help shorten the duration and severity of cold and flu-like symptoms, and a new test tube laboratory study results suggest that Carragelose could also reduce the risk of an infection with SARS-CoV-2, the virus which causes COVID-19.

Could this seaweed based cold remedy stop COVID-19 infection? (Image: Boots / Swansea University)

These promising results will be further validated in a new clinical trial, ICE-COVID, which will investigate whether Dual Defence can either prevent COVID19 infection or reduce severity of symptoms in humans compared with placebo. Professor Ron Eccles, cold and flu expert and former director of the Common Cold Centre at Cardiff University is co-investigator on the research study and will work closely with the Chief Investigators at Swansea University, Professor Iain Whitaker, Surgical Specialty Lead for Health & Care Research Wales and Professor Hayley Hutchings, Co-Director of the Swansea Trials Unit.

Dr Zita Jessop, the Principal Investigator for the clinical trial and clinician scientist at Swansea University, whose MRC funded doctorate was based on biomaterial science.

Dr Jessop describes her motivation for setting up the clinical trial “After seeing the effects of this pandemic on colleagues caring for patients with COVID-19, we wanted to find a way for research to help protect frontline NHS staff. Previous studies highlighted the effectiveness of iota-carrageenan-based nasal sprays against coronaviruses, indicating promise against SARS-Cov-2. If the results of this randomised placebo-controlled clinical trial are positive as we expect, this has the potential to add an extra prevention strategy in the fight against COVID-19.”

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The research is taking place at Swansea University with test subjects from Swansea Bay NHS (Image: Boots / Swansea University)

Richard Evans, Executive Medical Director, Swansea Bay University Health Board added: “We’re delighted that Swansea Bay University Health Board is able to contribute to this research. Although the prospect of effective vaccines is now on the horizon, it’s still vitally important that we explore all opportunities to investigate new treatments for COVID-19 and we’re pleased to be playing a part in that global effort.”

Carragelose is a patented version of iota-carrageenan and is generated from consumable red seaweeds occurring naturally throughout the world. The ingredient is exclusively available in Boots Dual Defence Nasal Spray in the UK and Carragelose is patented and invented by Marinomed in Austria. It acts as a barrier by forming a gel to trap cold and flu virus particles as they enter the body, therefore reducing the likelihood of infection or reducing the amount of virus entering the body and therefore reducing the severity of symptoms.

It is anticipated that results of ICE-COVID will be published in March 2021.

(Lead image: Boots / Swansea University)


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Coronavirus

‘Vaccines are best way to help NHS ahead of challenging winter’ says Health Minister

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People eligible for booster COVID-19 vaccinations and flu jabs are encouraged to take up the offer ahead of a challenging winter for NHS Wales, the Health Minister has said.

In an updated COVID-19 vaccination strategy, being published today (Tuesday October 12), Health Minister Eluned Morgan confirms that the majority of people eligible will be offered their booster vaccination by December 31, 2021.

People who are severely immuno-suppressed will be offered a third dose of vaccine to provide them with as much protection as possible.  They will be prioritised for an urgent appointment at a time that’s right for them based on their treatment and the advice of their clinician.

The strategy also confirms that by November 1, 2021, offers will be made for;

  • one dose for all 12-15 year olds and,
  • a booster vaccination for care home residents and health and care staff.

Everyone in the Joint Committee on Vaccination and Immunisation (JCVI)’s 1-9 priority groups will be invited for a booster vaccination when it has been at least six months since their last dose. As before, invitation letters will be sent directly from health boards and people are requested not to contact their GP.

Health Minister Eluned Morgan said: “This winter will be incredibly difficult for our health service so it is vitally important for people to take up the offer of their COVID-19 and Flu vaccine if eligible to protect themselves and the NHS.

“Vaccinations for coronavirus are highly effective and protection against hospitalisation is estimated at around 95 per cent after the second dose. The flu vaccine will also protect people from serious complications and I encourage anyone who is eligible to get their flu vaccine regardless of their eligibility for a COVID-19 booster vaccine.

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“We have so far given more than 4.6 million COVID-19 vaccinations and 85 per cent of the over 16 population are fully vaccinated.

“There is no concern over the supply of any of the vaccines and we hope as many people as possible take up the offers to continue to protect those most vulnerable and the NHS.”

Health boards are already making good progress in providing the booster, vaccinating 16 and 17 year olds and 12-15 year olds, including those most of risk due to underlying health conditions.

We are also encouraging 12-15 year olds to have a conversation about having the vaccine with their family or trusted adult.

Most younger adults will only have received their second COVID-19 vaccine dose in late summer or early autumn and they will still have a high level of protection. The benefits of booster vaccination in this group will be considered when more information becomes available.

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The strategy also sets out that a digital booking system is being developed to allow people to book appointments online to try to make it as easy of possible for people to come forward at a time which suits them.

Appointments for first doses of COVID-19 vaccines are still available for anyone unvaccinated.

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Arts and Entertainment

COVID Pass for events and nightclubs in Wales start from today

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group of people in a concert

People in Wales must show a Covid Pass or demonstrate their Covid status to enter nightclubs and attend large events from today (11th October).

Businesses could be fined up to £10,000 and issued closure notices for non-compliance. Fines could also be issued for people faking test results or vaccine status.

Cases of coronavirus continue to be high across Wales, especially among younger adults the Welsh Government have warned.

The new law starting today mandates that all adults over-18 will need to show an NHS Covid Pass or a negative Covid test to enter certain premises:

  • Nightclubs and similar venues;
  • Indoor, non-seated events for more than 500 people;
  • Outdoor non-seated events for more than 4,000 people;
  • Any setting or event with more than 10,000 people in attendance.

The controversial law passed by just one vote, after Welsh Conservative minister Gareth Davies, who was attending the party’s conference in Manchester, couldn’t log onto Zoom to vote against the proposal.

Economy Minister, Vaughan Gething said: “Our fantastic vaccination programme continues to go from strength to strength but the pandemic is not over. Cases of remain high across Wales and, unfortunately, families across the country are losing loved ones to this awful virus.

“The clear advice from our scientific advisers is that we need to take early action now.

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“The Covid Pass is just one of a series of measures in place to help prevent people spreading and catching coronavirus while helping to keep the economy open. None of us want to see further lockdowns and for businesses to have to close their doors once again.

“Showing a Covid Pass is already part of our collective effort to keep businesses open, with some major events, such as the successful Green Man Festival, using it.

“Together, if we all continue to follow the clear guidelines we’re all used to by now, we’ll be doing everything we can to Keep Wales Safe.”

People who are fully vaccinated in Wales can already download the NHS Covid Pass to securely show and share their vaccine status. It also allows people to show they have had a negative lateral flow test result within the last 48 hours.

Only people attending these venues and events will need to show their Covid status. Staff working or volunteering in these venues are encouraged to take lateral flow tests twice a week to check they do not have the virus. Workplaces are required by law to undertake Covid risk assessments, and to put reasonable measures in place to ensure staff safety.

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The Welsh Government say that Covid passes have been used successfully in many venues and events in Wales throughout the summer.

The First Minister confirmed last week that Wales will remain at alert level zero for the next three weeks. Plans are in place to respond to a challenging winter ahead with both coronavirus and seasonal flu both in circulation.

Welsh Government Ministers are continuing to encourage people to take steps to reduce the spread of the virus by continuing to work from home whenever possible, ensuring they take up the offer of a Covid vaccine, keeping your distance, isolating and taking a PCR test if you have symptoms, and wearing a face covering in indoor public places and on public transport.

The Welsh Government say they will use the current enforcement regimes for monitoring compliance – this means businesses and events will need to ensure their proposed arrangements to comply with the Covid pass regulations are included in their risk assessments, and reasonable measures to ensure compliance.

Penalties for non-compliance will include:

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  • a premises improvement notice or premises closure notice;
  • a fixed penalty notice and a maximum fine for businesses of £10,000.

In addition, it is now an offence for a person to provide false or misleading evidence of vaccination or testing status where that evidence is required as part of the requirement for holding a Covid pass.

(Lead image: Mark Angelo Sampan / Pexels.com)

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Coronavirus

First Minister unveils new plan to keep Wales open and safe during “challenging” winter ahead

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The First Minister, Mark Drakeford, will today (Friday 8 October) publish new plans to help keep Wales open and safe during the difficult autumn and winter months ahead.

The Welsh Government is publishing an updated Coronavirus Control Plan, which outlines the key actions, which could be put in place to control the spread of the virus.

Wales will remain at alert level zero for the next three weeks, following the latest review of the coronavirus regulations. This means all businesses are open and Wales has the lowest level of restrictions.

Speaking ahead of his press conference, First Minister Mark Drakeford said: “We are facing a challenging winter ahead – coronavirus hasn’t gone away and flu is forecast to return this winter.

“Vaccination is the best defence we have against coronavirus – the more people who are fully vaccinated, the better our chances of controlling the spread of this awful virus.

“We will continue to focus our efforts on increasing take up of the Covid-19 vaccine across the age and priority groups and rolling out the booster vaccine too. We also encourage everyone who is eligible, to have their flu jab this year.

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“There is also a range of other measures we can all take to help protect ourselves and our loved ones, such as washing our hands, reducing the number of people we meet and wearing a face covering in indoor public places.

“These measures have helped keep us safe throughout the pandemic and they will also help to protect us from other winter viruses, such as flu and other respiratory infections.”

The latest version of the Coronavirus Control Plan sets out two planning scenarios for the pandemic over the winter – in the first, called Covid Stable, Wales remains at alert level zero through the autumn and winter, with all businesses able to open.

This is thought to be the most likely scenario for the future, as we become used to living with coronavirus and we gradually move out of the pandemic to a position where the virus becomes a seasonal illness.

Under this scenario, if case rates fall, measures could be relaxed further in response, and if they rise, some existing measures could be strengthened to protect people’s health.

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The second planning scenario, called Covid Urgent, is designed to deal with any sudden changes to the situation, caused by the emergence of a new, fast-spreading variant or if vaccine immunity levels fall, causing a rise in pandemic pressures, which risk overwhelming the NHS.

The Welsh Government says that in such a scenario, the alert level system and restrictions would be used proportionately, but as a last-resort means, to protect people’s health, control the spread of infections and to protect the NHS.

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