The team sees a host of internationals return to the fold with young fly-half Dan Edwards possibly in line to make his debut off the bench.
Nicky Smith starts at loosehead, with Dewi Lake lining up at hooker and Ben Warren completing the front three.
Rhys Davies partners with Adam Beard in the second row. In the back row, Harri Deaves gets the start following on from his impressive display against the Sharks, whilst Justin Tipuric returns as captain. Morgan Morris starts at eight after his man of the match performance last week.
Reuben Morgan-Williams lines up at scrum half, with Jack Walsh starting at 10. Owen Watkin partners with Keiran Williams in the centre.
In the back three, Max Nagy starts at full back, with Mat Protheroe and Luke Morgan on the wings.
George North also returns and takes up a place on the bench.
Ospreys XV to face Glasgow Warriors:
15. Max Nagy 14. Luke Morgan 13. Keiran Williams 12. Owen Watkin 11. Mat Protheroe
10. Jack Walsh 9. Reuben Morgan-Williams
1. Nicky Smith 2. Dewi Lake 3. Ben Warren 4. Rhys Davies 5. Adam Beard 6. Harri Deaves
7. Justin Tipuric (captain) 8. Morgan Morris
Replacements:
16. Ethan Lewis 17. Garyn Phillips 18. Tom Botha 19. James Fender 20. James Ratti
21. Luke Davies 22. George North 23. Dan Edwards
[Lead image: Ospreys Rugby]
