Officers executed a warrant on the property at Queen Street in Neath as a result of community intelligence.
Police remain at the property while investigations continue to be carried out.
Inspector Lindsey Sweeney from South Wales Police said: “An investigation is continuing, and we are appealing to anyone who may have seen suspicious activity at the property to come forward.
“Members of the community should report any information in relation to drugs and all information will be treated confidentially.”
Police are asking anyone with information to contact them or Crimestoppers anonymously on 0800 555111 quoting occurrence number 2300016250.
(Lead image: South Wales Police)